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(Ashwood et al., 2011), observed significantly higher level of cytokines, specifically IL-1, IL-6, IL-8, IL-12p40,in the plasma of 97 children aged 2-5, if compared to the levels of age-matched children of the control group or children with other developmental conditions

Finally, this treatment reduced the levels of the pro-inflammatory cytokines IL-1 and IL-33 while maintaining anti-inflammatory cytokine IL-10 levels, and maintained the levels of endogenous antioxidants in the colons of colitic mice (173)( Supplementary Table 1 )

Distinct attributes such as hypoxia, acidic conditions, and elevated mesenchymal pressure can establish physical impediments to traditional drug delivery and treatment

A gel with 0.06% BV did not cause photosensitive dermatitis, as proven in animals (Han et al., 2017)